摘要 |
SUBSTITUTED 1,3-DIAMINOPROPANES N'-Acyl-N-alkyl-1,3-diaminopropanes of formula R1CONH(CH2)3NHR2 where R1 is R- or RNH where R is a substituted or unsubstituted hydrocarbon group and R2 is alkyl) are prepared by selectively acylating N-alkyl-1,3-diaminopropanes. In the process a N-alkyl 1,3-aminopropane is reacted with an aldebyde to form a hexahydropyrimidine, the hexahydropyrimidine is acylated and the acylated hexahydropyrimidine is then hydrolysed to give the product.
|