| 发明名称 |
2H-CHROMENE COMPOUND AND DERIVATIVE THEREOF |
| 摘要 |
Disclosed is a compound which has an excellent S1P1 agonistic activity and is particularly useful as an active ingredient for a prophylactic and/or therapeutic agent for diseases induced by undesirable lymphocyte infiltration or diseases induced by abnormal proliferation or accumulation of cells. Specifically disclosed are a 2H-chromene compound and a derivative thereof, each of which has an S1P1 agonistic activity and can be used particularly for the prevention and/or treatment of diseases induced by undesirable lymphocyte infiltration or diseases induced by abnormal proliferation or accumulation of cells. (see formula I) |
| 申请公布号 |
CA2745356(C) |
申请公布日期 |
2016.12.20 |
| 申请号 |
CA20092745356 |
申请日期 |
2009.12.04 |
| 申请人 |
ASTELLAS PHARMA INC. |
发明人 |
HARADA, HIRONORI;HATTORI, KAZUYUKI;FUJITA, KAZUYA;IMADA, SUNAO;MOROKATA, TATSUAKI |
| 分类号 |
C07D403/12;A61K31/397;A61K31/4025;A61K31/403;A61K31/404;A61K31/41;A61K31/4155;A61K31/427;A61K31/4433;A61K31/4436;A61K31/4439;A61K31/453;A61P1/00;A61P1/16;A61P1/18;A61P3/10;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P19/02;A61P21/04;A61P25/00;A61P29/00;A61P35/00;A61P37/06;A61P43/00;C07D405/06;C07D405/14;C07D409/06;C07D409/12;C07D409/14;C07D413/14;C07D417/14 |
主分类号 |
C07D403/12 |
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