发明名称 ABUSE-PROOFED DOSAGE FORM
摘要 The invention relates to a dosage that is thermoshaped without being extruded and that is safeguarded from abuse, comprising at least one synthetic or natural polymer having a breaking strength of at least 500 N in addition to one or more active substances that could be subject to abuse and optionally physiologically acceptable adjuvants. The invention also relates to a corresponding method for producing said dosage form.
申请公布号 US2016374963(A1) 申请公布日期 2016.12.29
申请号 US201615257255 申请日期 2016.09.06
申请人 GRÜNENTHAL GMBH 发明人 ARKENAU-MARIC ELISABETH;BARTHOLOMÄUS JOHANNES;KUGELMANN HEINRICH
分类号 A61K31/135;B29C47/40;B29C47/00;A61K9/20;B29C47/06 主分类号 A61K31/135
代理机构 代理人
主权项 1. An abuse-proofed dosage form thermoformed by extrusion without discoloration, wherein, in addition to one or more active ingredients with abuse potential (A) optionally together with physiologically acceptable auxiliary substances (B), it contains at least one synthetic or natural polymer (C) and optionally at least one wax (D), wherein component (C) and the optionally present component (D) exhibit a breaking strength of at least 500 N.
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