发明名称 |
CALCIUM CITRATE MALATE COMPOSITION |
摘要 |
A metastable complex of calcium, citrate and malate is disclosed. This material is highly bioavailable, and is soluble in both neutral and acid solutions. The salt is prepared by the reaction of calcium carbonate, calcium hydroxide or calcium oxide with citric and malic acids in aqueous solution. The reaction mixture is dried at a temperature of less than 100 DEG C, and the resultant solid is a metastable solid. The solid can be ground to reduce the particle size for easier tabletting or adding to foods and beverages. Preferred salts are neutral and acidic salts which can be expressed by molar ratios. |
申请公布号 |
WO9119692(A2) |
申请公布日期 |
1991.12.26 |
申请号 |
WO1991US03779 |
申请日期 |
1991.05.30 |
申请人 |
THE PROCTER & GAMBLE COMPANY |
发明人 |
FOX, MARY, MORA;HECKERT, DAVID, CLINTON;LUHRSEN, KENNETH, RAY |
分类号 |
A61K31/19;A61P1/02;A61P3/00;A61P3/14;A61P43/00;C07C51/41;C07C59/245;C07C59/265 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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