发明名称 |
AMINO ACID DERIVATIVES |
摘要 |
RAN 4019/111 The compounds of the formula I wherein A, B, X, Y, R1, R2, R3. R4 and R5 have the significance given in claim 1, in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diastereomeric racemates as well as pharmaceutically usable salts thereof inhibit the activity of the natural enzyme renin and can accordingly be used in the form of pharmaceutical preparations in the control or prevention of high blood pressure and cardiac insufficiency. They can be manufactured according to various methods which are known per se.
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申请公布号 |
CA2044564(A1) |
申请公布日期 |
1991.12.29 |
申请号 |
CA19912044564 |
申请日期 |
1991.06.13 |
申请人 |
HOFFMANN-LA ROCHE (F.) CO. AKTIENGESELLSCHAFT |
发明人 |
BRANCA, QUIRICO;HEITZ, MARIE-PAULE;MULLER, MARCEL;NEIDHART, WERNER;STADLER, HEINZ;VIEIRA, ERIC;WOSTL, WOLFGANG |
分类号 |
A61K31/435;A61K31/495;A61K31/50;A61P9/00;A61P9/12;C07D263/06;C07D471/04;C07D487/04;(IPC1-7):C07D487/04 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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