发明名称 |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF HYPERGLYCEMIA AND METABOLIC SYNDROME |
摘要 |
The compositions and compounds of Formula I, Formula II, Formula III which includes a salts of polyunsaturated fatty acids in a molecular conjugate form with an amino acid L-leucine or its polymorphs, enantiomers, stereoisomers, solvates, and hydrates thereof. These salts may be formulated as pharmaceutical compositions. The pharmaceutical compositions may be formulated for oral administration, delayed release or sustained release, transmucosal, syrup, topical, parenteral administration, injection, subdermal, oral solution, rectal administration, nanoparticle, buccal administration or transdermal administration. Such compositions may be used to treatment of hyperglycemia, metabolic syndrome, diabetes, pre-diabetes, lowering triglycerides or its associated complications. |
申请公布号 |
US2016318850(A1) |
申请公布日期 |
2016.11.03 |
申请号 |
US201514938197 |
申请日期 |
2015.11.11 |
申请人 |
Alapati Mohan Murali |
发明人 |
Alapati Mohan Murali |
分类号 |
C07C233/31 |
主分类号 |
C07C233/31 |
代理机构 |
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代理人 |
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主权项 |
1. A compound of Formula I: or salts, pharmaceutically acceptable salts, hydrates, solvates, crystals, enantiomers or stereoisomers thereof, or mixtures thereof, wherein: RH independently represents at least one of Lysine, L-lysine, arginine, L-arginine, betaine, choline, diethanolamine, diethylamine, ethanolamine, ethylenediamine, glucosamine, piperazine, pyridoxine, pyridoxamine, triethanolamine, tromethamine or meglumine. |
地址 |
Andhra Pradesh IN |