发明名称 5-phenyl-1H-pyrazol-4-propionic acid derivatives, compositions and use
摘要 Compounds of formula I <IMAGE> (I) wherein R1 is alkyl, alkoxy, alkylthio, alkylamino, aryl, aryloxy, arylthio, arylamino, aralkyl, aralkoxy, aralkylthio or aralkylamino, R2 and R3 are each independently hydrogen, halogen, hydroxy, mercapto, nitro or amino or have the meanings given for R1, and X is -NH2, -NH-OH, -N(R4)OH, -NH-NH2 or -NH-N=C(R4)R5, wherein R4 and R5 are each alkyl, in free form or pharmaceutically acceptable salt form, have pharmaceutical utility, in particular in the treatment or prophylaxis of asthma, or in the treatment of inflammation or psoriasis.
申请公布号 US5141951(A) 申请公布日期 1992.08.25
申请号 US19910800781 申请日期 1991.11.27
申请人 SANDOZ LTD. 发明人 WUETHRICH, HANS-JUERG
分类号 A61K31/415;A61P1/04;A61P11/00;A61P29/00;C07D231/12 主分类号 A61K31/415
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