| 摘要 |
A process for preparing L-phenylalanine methylester comprises (a) adding H2SO4 as a catalyst in excess amount of methanol and inserting L-phenylalanine, (b) reacting the mixture at 64.7-85 deg.C for 2 hrs under reflux, (c) neutralyzing the obtd. L- phemylalanine methylester sulfate with alkali soln., and (d) extracting it with an organic solvent selected from chloroform, toluene or ethylacetate. Pref. the molar ratio of methanol to L- phenylalamine is 10:1, and the using amount of H2SO4 to L- phenylalanine is 4 equivalene or more.
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