Receptors for bombesin-like peptides are solubilized and purified in active form. The amino acid sequence and DNA encoding various subtypes of the receptors are disclosed. Uses of the purified receptor gene and polypeptide are disclosed, including means for screening for agonists and antagonists of the receptor ligands, for producing diagnostic or therapeutic reagents, and for producing antibodies. Therapeutic or diagnostic reagents and kits are also provided.
申请公布号
WO9216623(A3)
申请公布日期
1992.10.29
申请号
WO1992US02091
申请日期
1992.03.13
申请人
BERLEX LABORATORIES, INC.;THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS