| 摘要 |
PURPOSE:To provide the stable chronic fatigue syndrome therapeutic agent containing a polysaccharidte having beta-1,3-glucoside bonds in the main chain as an active ingredient and not having adverse actions. CONSTITUTION:The agent contains a polysaccharide having the main chain comprising beta-1,3-gluco sidebonds, preferably sizofiran produced by Schizophyllum or lentinan produced by Lentinus as an active ingredient. The polysaccharide is usually suitably administered in a dose of 0.5-1000mg per day for an adult once to several times in a day when orally administered. The sizofiran is produced outside the cells by the culture of the Schizophyllum, but preferably converted into a low molecule having a mol.wt. of <=1000000 (by the ultrasonic treatment or high shearing force treatment of the polysaccharide) without changing the basic structure of the polysaccharide, because it is difficult to purify the polysaccharide due to its high viscosity and thixotropy. |
