| 摘要 |
Galenic compositions can be applied into the skin thanks to novel micro-aggregates as excipients. The object of the invention is to make available for the therapeutical and diagnostic use on the skin or for systemic application pharmacological active substances in a biologically and chemically inert excipient, allowing deeper penetration into the skin or the transcutaneous transport. For that purpose, a galenic composition for topical use contains asymmetrical lamellary aggregates consisting of phospholipids, pharmacological active substances and fluorocarbons or fluorocarbon mixtures, the amount of fluorocarbons lying in a range from 1 to 100 % by weight/volume, in a pharmaceutical excipient appropriate for topical use. The galenic composition is prepared by emulsifying its components and by using it in salves, creams , lotions, pastes, gels, powders or on a plaster or bandage, or in a spray. |
