METHODS OF MEASURING TOTAL RETINAL BLOOD FLOW USING EN FACE DOPPLER OCT

摘要

Methods of performing en face Doppler total retinal blood flow measurement are disclosed. The methods involve obtaining a set of structural OCT scans; calculating a noise-reduced set of Doppler phase shift images by dividing the full spectrum OCT fringe data into a set of narrower filtered frequency bands for phase shift calculation; removing bulk motion along a depth direction; detecting retinal vessels in the set of images; applying a phase unwrapping algorithm to the images; classifying the vessels as veins and arteries; and calculating total retinal blood flow based on that classification.

主权项

1. A method of measuring retinal blood flow using optical coherence tomography (OCT), comprising:
receiving an OCT scan dataset of a region of the eye; generating a reflectance OCT dataset, the reflectance OCT dataset comprised of a set of en face reflectance images; generating a Doppler OCT dataset, the Doppler OCT dataset comprised of a set of en face Doppler images; detecting a set of vessels in the set of en face Doppler OCT images; applying a phase unwrapping algorithm to the set of en face Doppler OCT images; identifying a set of vein branches in the set of vessels; determining an optimized en face plane for each of the vein branches; and calculating a blood flow on the optimized en face plane for each of the vein branches;