| 发明名称 |
Enzymes for the production of 2-keto-L-gulonic acid |
| 摘要 |
Mutants of 2,5-diketo-D-gluconic acid reductase A, an enzyme used to produce 2-keto-L-gulonic acid, a precursor of ascorbic acid (vitamin C) are prepared by site-directed mutagenesis. These mutants have increased catalytic activity, increased expression levels, and/or enhanced temperature stability.
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| 申请公布号 |
US5376544(A) |
申请公布日期 |
1994.12.27 |
| 申请号 |
US19920941414 |
申请日期 |
1992.09.08 |
| 申请人 |
RUTGERS THE STATE UNIVERSITY OF NEW JERSEY |
发明人 |
LAZARUS, ROBERT A.;HURLE, MARK;ANDERSON, STEPHEN;POWERS, DAVID B. |
| 分类号 |
C12N15/09;C12N1/21;C12N9/04;C12N15/53;C12N15/74;C12P7/60;C12R1/01;C12R1/02;C12R1/18;(IPC1-7):C12N9/04 |
主分类号 |
C12N15/09 |
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