| 摘要 |
<p>A compound of formula (I) is disclosed. R13 represents hydrogen, NH¿2?, C1-4 alkyl, C1-4 alkylamino or di(C1-4) alkylamino-; Y represents CH or N; Y' represents (a) CRη'R?z'¿ with Rη' and Rz' hydrogen, C¿1-6? alkyl, C3-8 cycloalkyl or C1-6 alkyl substituted with C3-8 cycloalkyl, or (b) N substituted with OR?14 with R14¿ representing H, C¿1-4? alkyl or C1-4 alkyl substituted with COOH. Ar represents (II). One of R?1 and R2¿ independently represents H, W as defined in the description or one of the groups (a) through (d) in the description, and the other represents H or W. Pharmaceutical compositions and methods of use are also included.</p> |
