This invention relates to novel 3-aminopyridines of the formula wherein B1, B2 and R1 to R6 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
申请公布号
HK1190707(A1)
申请公布日期
2016.11.18
申请号
HK20140103757
申请日期
2014.04.18
申请人
F. HOFFMANN LA ROCHE AG
发明人
BISSANTZ, Caterina;DEHMLOW, Henrietta;ERICKSON, Shawn David;KARNACHI, Prabha Saba;KIM, Kyungjin;MARTIN, Rainer, E. E;MATTEI, Patrizio;OBST SANDER, Ulrike;PIETRANICO-COLE, Sherrie Lynn -;RICHTER, Hans;ULLMER, Christoph