摘要 |
<p>A filter housing in the form of a centrifugal concentrator filter unit (3) is dimensioned to be fully containable in a conventional centrifuge tube (2) when sealed with a cap (4) to provide a closed system centrifugal concentrator adapted to concentrate solution without creating external aerosol or fluid contamination. In accordance with a principle aspect of the invention the filter housing (3) comprises two mating parts (5, 6) which retain a filter element (7) between confronting formations of the two parts (5, 6). End wall formations of the two housing parts (5, 6) cooperate to define a capillary channel (16) into which a watery free-flowing cyanoacrylate polymer adhesive or sealant can be introduced from ledge (12A) through aperture (12). The adhesive will flow around the channel (16) by capillary action to form a bead seal (19) between the filter element (7) and the two parts (5, 6). The principle aspect of the invention is applicable to two-part filter housings generally. Conveniently and in accordance with other aspects of the invention, a first one of the two parts is provided by a generally cylindrical filter tube (5) which is a loose or sliding fit in the centrifuge tube (2) and which provides a filter reservoir between an open end of the filter tube and the filter element in the form of permeable filter membrane (7) disposed across an opening at or near the other end of the tube, and the second housing part is provided by elongate spacer member (6) extending from the filter tube oppositely to the reservoir which in use abuts a closed end portion of the centrifuge tube (2) to space the filter membrane (7) therefrom and to define a filtrate collection vessel of a predetermined volume at the closed end of the centrifuge tube (2).</p> |