| 摘要 |
<p>Compounds that are synthetically inexpensive to make relative to the naturally occurring selectin ligands and that retain selectin binding activity are described that have a three-dimensionally stable configuration for sialic acid and fucose, or analogs or derivatives of these groups, such that sialic acid and fucose are separated by a linker that permits binding between those groups and the selectins, such compounds being represented by general structural formulae (I) and (II), where W is selected from a group including structures (a-d), wherein A is preferably sialic acid, and B is preferably fucose. The other radicals in said formulae are outlined in the description.</p> |
