| 摘要 |
PURPOSE: To obtain an active oxygen eliminating agent containing, as active ingredient, a new exanthone compound extracted from Garcinia-subelliptica, excellent in lipoperoxide-inhibitory action, free radical-eliminating action and superoxide-eliminating action, thus useful for preventing/treating various diseases due to an excess of active oxygen. CONSTITUTION: This active oxygen-eliminating agent contains, as active ingredient, 1,4,5-trihydroxyxanthone of formula I, or a xanthone compound of formula II, III or IV. The above xanthone compound is obtained by grinding a dried material of Garcinia-subelliptica belonging to Hypericum plant and subjecting the resultant dry powder to extraction with an organic solvent such as methanol or ethanol followed by isolation by column chromatography using a carrier such as silica gel. |
