发明名称 RETINOID COMPOSITION
摘要 PURPOSE: To provide a skin-care composition containing an O/W-type emulsion liquid and retinoids and having excellent physical stability of the emulsion liquid and chemical stability of the active components. CONSTITUTION: An O/W-type emulsion liquid is incorporated with a retinoid selected from vitamin A alcohol, vitamin A aldehyde, retinyl acetate, retinyl palmitate and their mixture and further with a stabilizer system selected from (a) an oil-soluble antioxidant (e.g. butylated hydroxytoluene), (b) a chelating agent (e.g. ethylenediaminetetraacetic acid) and an oil-soluble antioxidant, (c) a chelating agent and (d) an antioxidant and a chelating agent existing in each of the oil phase and the water phase of the emulsion liquid. At least 70% of the retinoid remains after adjusting the composition to pH4-10 and storing at 40 deg.C for 13 weeks. The oil phase of the composition is composed of saturated oil or fat and has a C value of <=1,200. The content of the retinoids in the composition is 0.001-5wt.%.
申请公布号 JPH08193019(A) 申请公布日期 1996.07.30
申请号 JP19950264586 申请日期 1995.09.07
申请人 JOHNSON & JOHNSON KK 发明人 YAMAMOTO NORIHIRO;KAZAMA SATORU;JIYUUCHIEN RIYUU;JIYONASU WANGU
分类号 A45D34/00;A61K8/00;A61K8/02;A61K8/06;A61K8/23;A61K8/29;A61K8/31;A61K8/33;A61K8/37;A61K8/39;A61K8/41;A61K8/46;A61K8/49;A61K8/67;A61K8/89;A61K8/891;A61K8/92;A61K8/97;A61Q19/00;B32B15/08;B32B27/36;B65D30/02;B65D83/38 主分类号 A45D34/00
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