发明名称 Detecting antibodies against human papilloma virus proteins - for early diagnosis of HPV-mediated carcinoma
摘要 <p>Antibodies (Ab1) directed specifically against HPV (human papilloma virus) proteins (A) are detected in body fluids by: (i) incubating a native, carrier-bound (A) with the sample; and (ii) reacting bound Ab1 with: (a) labelled antibody (Ab2) directed against Ab1; or (b) unlabelled Ab2 and then third labelled antibody (Ab3) directed against Ab2. Also new are (A) made by refolding the corresponding denatured protein.</p>
申请公布号 DE19627031(A1) 申请公布日期 1997.01.09
申请号 DE1996127031 申请日期 1996.07.04
申请人 DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS, 69120 HEIDELBERG, DE 发明人 ZENTGRAF, HANSWALTER, DIPL.-BIOL. DR., 69115 HEIDELBERG, DE;FREY, MANFRED, DIPL.-CHEM. DR., 68259 MANNHEIM, DE;VELHAGEN, IRIS, DIPL.-BIOL. DR., 68723 SCHWETZINGEN, DE;MARTENS, REGINA, 69207 SANDHAUSEN, DE;MESCHEDE, WOLFGANG Z., DIPL.-BIOL., 69121 HEIDELBERG, DE;PAWLITA, MICHAEL, DR., 74927 ESCHELBRONN, DE;BRASPENNING, JORIS A.C.J.M., DIPL.-BIOCHEM., 69436 SCHOENBRUNN, DE
分类号 C07K14/025;G01N33/543;G01N33/569;G01N33/574;G01N33/68;(IPC1-7):G01N33/543;G01N33/62;C12Q1/70;C07K14/01;G01N33/576 主分类号 C07K14/025
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