TERTIARY AMINES

摘要

Tertiary amines of the formula <IMG> I wherein A1 is alkyl or alkenyl and A2 is cycloalkyl, cycloalkyl-alkyl or an optionally substituted alkyl or alkenyl group and, where A1 is alkyl, A2 can also be OH, A3 and A4 are hydrogen or alkyl or A1 and A2 or A3 together form an optionally substituted alkylene, alkenylene or alkadienylene group A1-A2 or A1-A3, whereby in a group A1-A2 or A1-A3 up to 2 C atoms can be replaced by one (or two) N atom(s) and/or by a group N-alkyl, p = 1 and L is phenylene, or alkylene or alkenylene which is bonded to M directly or via O, NH or N(alkyl or alkanoyl) and which has a total of up to 11 C atoms and at least 4 or, respectively, 3 C atoms between the two free valencies or L is cycloalkylene-alkylene or p = O and L is C6-11-alkenylene or C6-11-alkadienylene bonded to T, M is thienylene, pyridylene, optionally substituted 1,4-phenylene or a group of the formula <IMG> (M1) q is 1 or 0, T is CO, CH(R3), C(R4,R5) or C=NOR6 and, where M is a group M1 and q = O, T can also be SO2, R3 is OH, F, alkoxy or alkanoyloxy, R4 is OH and R5 is alkyl, alkenyl, alkynyl, cycloalkyl or CF3 or R4 and R5 together are the group CH2, CH2O or CH2CH2, R6 is H, alkyl or alkenyl, Q is cycloalkyl, C(R7,R8), optionally substituted phenyl or a straight-chain alkyl, alkenyl, alkadienyl or alkatrienyl group Q' with 0 to 3 methyl substituents and a total of 6 to 13 C atoms and R7 and R8 are C5-11-alkyl, C5-11-alkenyl or C5-11- alkadienyl, and acid addition salts thereof have antimycotic and cholesterollowering activity.