| 摘要 |
<p>Primary and secondary osteoporosis in a female or a male mammal in any age treated by administering thereto a nitric oxide synthase substrate, a nitric oxide donor or both, optionally; in further combination with one or more of an estrogen, a progestin, a bisphosphonate, an anabolic steroid, testosterone, a flavinid, vitamin D analogue or a calcitonin. Nitric oxide substrate or donor also can be combined with one or more of the other medication acting on bone, such as bisphosphonate, calcitonin, fluoride, androgen, vitamin D analogue, and other novel therapeutic agents. Either nitric oxide donor or substrate by itself or in combination with other medications as described above can be used in both males and females, for prevention and treatment of osteopenia or osteoporosis, and other metabolic bone disorders.</p> |
