| 摘要 |
<p>The invention concerns a compound of formula (I), wherein, for example: R1 is of the formula -NHC(=O)(1-4C)alkyl; R?2 and R3¿ are hydrogen or fluoro; R?4 and R5¿ are hydrogen or methyl; ⊃A-B- is of the formula ⊃C=CH-, ⊃CHCH¿2?, or ⊃C(OH)CH2- (⊃ represents two single bonds); D is O, S, SO, SO2 or -NR?7¿; wherein R7 is hydrogen, R?10CO-, R10SO¿2-, RaOC(Rb)=CH(C=O)-, RcC(=O)C(=O)-, RdN=C(Re)C(=O)-, RfNHC(Rg)=CHC(=O)- or R?14CH(R13)(CH¿2)m-; wherein R10 is (1-6C)alkyl [optionally substituted by, for example, hydroxy or (1-6C)alkanoyl], R11C(O)O(1-6C)alkyl or R12O-; wherein R 11 is optionally substituted (1-6C)alkyl; R12 is optionally substituted (1-6C)alkyl; R?a, Rb, Rc, Rd, Re, Rf, Rg¿ are (1-6C)alkyl; m is 0 or 1; R13 is cyano; R14 is hydrogen or (1-4C)alkyl; ⊃X-Y- is of the formula ⊃C=CH- or ⊃CHCH¿2?-; and pharmaceutically acceptable salts thereof; processes for the preparation; pharmaceutical compositions containing them and their use as antibacterial agents.</p> |
