发明名称 SUBSTITUTED IMIDAZOLES AS MODULATORS OF MULTI-DRUG RESISTANCE
摘要 This invention relates to compounds of Formula 1 which are pharmacologically useful for the treatment of cancer through sensitization of multi-drug resistant cancer cells to chemotherapeutic agents. (see fig.I) wherein R1, R2, R3, and R4 are, for example, alkyl, aryl, etc., which are defined more specifically hereinafter.
申请公布号 CA2179086(A1) 申请公布日期 1997.12.14
申请号 CA19962179086 申请日期 1996.06.13
申请人 ONTOGEN CORPORATION 发明人 MJALLI, ADNAN M.;SARSHAR, SEPEHR
分类号 A61K31/41;A61K31/435;A61K31/495;C07D233/64;C07D401/00;C07D403/00;C07D405/00;C07D409/00;C07D413/00;C07D417/00;C07D473/00;(IPC1-7):C07D233/64 主分类号 A61K31/41
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