PROCESS FOR PREPARING OF A SUPERFICIAL THERAPEUTIC SYSTEM CONTAINING ANTINEOPLASTIC AGENT, PARTICULARLY 5-FLUORO URACIL

摘要

The invention refers to the procedure for the production of the superficial therapeutic system which consists of an impermeable back layer, a matrix that contains the active substance and of a re-detachable protective layer. It is marked in the way that the following components of the matrix a. antineoplastic active substance, b. self-adhesive polyacrylate, c. water absorber and possibly d. non-adhesive hydrophile polyacrylate, e. softener and/or accelerator of the penetration are homogeneously mixed, possibly with dissolving in a solvent. The homogeneous mixture is applied to the impermeable back layer, the solvent is possibly removed and then the layer of the matrix is covered with the protective layer.