| 摘要 |
FIELD: organic chemistry. SUBSTANCE: new 1,2,4-oxadiazolylphenoxyalkylisoxazoles are synthesized by interaction of amideoxime (N-hydroxycarbooxyimideamide) with acid haloidanhydride or alkylhaloidformate in the presence of organic base in an inert solvent. Product: 5-{3-[2,6-dimethyl-4-(5-trifluoromethyl-1,2,4-oxadiazole-3- -yl)-phenoxy] -propyl} -3-methylisoxazole, m. p. is 61-62 C. Compounds can be used in compositions against picornoviruses. EFFECT: improved method of synthesis, enhanced effectiveness. 8 cl, 1 tbll
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