| 摘要 |
<p>The invention concerns a combined product comprising at least a substance breaking up a cell extracellular matrix and at least a nucleic acid of interest, to be administered simultaneously, consecutively or spread over time, said nucleic acid being carried by an infectious viral particle or in the form of a synthetic vector. The invention also concerns the use of said product for therapeutic or vaccine purposes to prepare a medicine for treating the human or animal body using gene therapy and the use of a substance breaking up the extracellular matrix to improve the transfer and/or the expression of said nucleic acid of interest in a host cell or organism.</p> |
