| 发明名称 |
COMPUESTOS HETEROCICLICOS INHIBIDORES DE METALOPROTEASAS |
| 摘要 |
The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a structure according to Formula (I) as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable alkoxyamide, ester, acyloxyamide, or imide thereof. Also disclosed are compounds, pharmaceutical compositions and methods of treating diseases characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.
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| 申请公布号 |
PE109298(A1) |
申请公布日期 |
1999.01.31 |
| 申请号 |
PE19970000772 |
申请日期 |
1997.08.28 |
| 申请人 |
THE PROCTER AND GAMBLE COMPANY |
发明人 |
TAIWO, YETUNDE OLABISI;ALMSTEAD, NEIL GREGORY;BRADLEY, RIMMA SANDLER;GARRETT, GARY STEVEN;MARLIN II, JOHN EMORY;MCIVER, JOHN MCMILLAN;DE, BISWANATH;WANG, ZHE |
| 分类号 |
A23G4/00;C07D207/48;A61K8/00;A61K8/49;A61K31/395;A61K31/40;A61K31/4439;A61K31/445;A61K31/454;A61K31/5377;A61P1/02;A61P9/00;A61P17/00;A61P19/08;A61P27/02;A61P29/00;A61P43/00;A61Q11/00;C07D207/36;C07D211/96;C07D213/16;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D417/04;C07D417/06;C07D417/12;C07D417/14 |
主分类号 |
A23G4/00 |
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