发明名称 COMBINED ELECTROPORATION AND IONTOPHORESIS APPARATUS FOR DRUG AND GENE DELIVERY
摘要 <p>An apparatus for transdermal molecular delivery, comprises a first electrode assembly having an anode and a cathode in closely spaced relation for engaging the stratum corneum through which to apply an electric field, first power supply including a first circuit connected to the first electrode assembly for applying a pulsed electric field of sufficient amplitude to induce pores in the stratum corneum, a second electrode assembly spaced from the first electrode assembly and comprising at least one of an anode and a cathode, second power supply including a second circuit connected to the first electrode assembly and the second electrode assembly for applying a low voltage continuous electric field of a preselected polarity and sufficient amplitude to induce migration of molecules through pores in the stratum corneum.</p>
申请公布号 WO1999022809(A1) 申请公布日期 1999.05.14
申请号 US1998006638 申请日期 1998.04.02
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