| 摘要 |
<p>Compounds represented by general formula (I), etc. which are useful as remedies or preventives for various diseases caused by active oxygen, for example, diabetic nephropathy, diabetic retinopathy, chronic nephretis, chronic heart diseases, Alzheimer's disease and arteriosclerosis. In said formula, G represents optionally substituted hydroxy, etc.; R1 represents linear lower alkyl, etc.; R2 represents optionally substituted linear lower alkyl, etc.; R3 represents optionally substituted lower alkyl, etc.; R4 represents lower alkyl, etc.; R5 represents -CH¿2-R?6 (wherein R6 represents aliphatic hydrocarbyl, etc.), -CH=CH-R7 (wherein R7 represents aliphatic hydrocarbyl, etc.) or -(CH¿2)n-R?8 (wherein n is an integer of 0 to 6; and R8 represents optionally substituted alicyclic hydrocarbyl); and ∩ represents a Z-conformation, etc.</p> |
