发明名称 Elevation of HDL cholesterol by 2-(4-chloro-1-arylbutylidene)-hydrazinecarbothioamides.
摘要 This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of formula (I), wherein R<1>, R<2> and R<3> are independently hydrogen, C1-C10 alkyl, or -(CH2)0-6Ar<1> where Ar<1> is phenyl, furanly, pyridinyl or thienyl, and Ar<1> is optionally substituted by halogen, cyano, nitro, C1-C6 alkyl, C1-C6 alkoxy, trifluoromethyl, C1-C6 alkoxycarbonyl, -CO2H or OH.
申请公布号 ZA9805152(B) 申请公布日期 1999.12.12
申请号 ZA19980005152 申请日期 1998.06.12
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 THOMAS JOSEPH COMMONS;CHRISTA L. MUSIAL;SUSAN CHRISTMAN
分类号 C07C337/08;C07D213/53;C07D333/22 主分类号 C07C337/08
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