NOVEL PREPARATION METHOD FOR DERIVATIVES OF 4-PHENYL-1,2,3,6- TETRAHYDROPYRIDINE AND THE INTERMEDIATE PRODUCTS ACTIVATED THEREBY,申请号CA19992275192-传众专利搜索

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发明名称	NOVEL PREPARATION METHOD FOR DERIVATIVES OF 4-PHENYL-1,2,3,6- TETRAHYDROPYRIDINE AND THE INTERMEDIATE PRODUCTS ACTIVATED THEREBY
摘要	L'invention a pour objet un procédé de préparation des composés de formule (I): <IMG> dans laquelle R1 représente un atome d'hydrogène ou un radical alkyle et R3 représente un radical alkyle, caractérisé en ce que l'on soumet un composé de formule (II). <IMG> à l'action d'un agent d'halogénation électrophile puis à l'action d'un agent d'halohydroxylation, puis à l'action d'une base, puis à l'action d'un agent de réduction diastéréosélective, puis à l'action d'un agent de réduction pour obtenir le composé de formule (I). Les produits de formule (I) sont des produits connus utiles notamment pour la synthèse de produits thérapeutiquement actifs. L'invention a également pour objet à titre de produits chimiques nouveaux certains des intermédiaires de synthèse.
申请公布号	CA2275192(A1)	申请公布日期	1999.12.18
申请号	CA19992275192	申请日期	1999.06.15
申请人	HOECHST MARION ROUSSEL	发明人	BRION, FRANCIS;RICHARD, CHRISTIAN
分类号	C07B57/00;C07D211/42;C07D211/70;C07D491/044;C07D493/04;(IPC1-7):C07D211/42	主分类号	C07B57/00
代理机构		代理人
主权项
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