发明名称 Fremgangsmåte for kontinuerlig fremstilling av transdermale terapeutiske plastre
摘要 A process for continuously manufacturing transdermal therapeutic patches having a backing layer, a pressure-sensitive adhesive drug reservoir layer, and a removable protective layer, whereby loss of active substances during fabrication of the patches is minimized, said process being characterized in that, in a tape-like laminate having a pressure-sensitive adhesive backing layer (1) and a removable protective layer (3), single quadrangular pressure-sensitive adhesive drug reservoir sections (2) are inserted one after the other in the longitudinal direction between the layers (2,3); the clearance between said drug reservoir sections remains constant in the longitudinal direction; their width is calculated such that the backing layer (1) and the removable protective layer (3) project beyond both sides of said sections; the pressure-sensitive adhesive backing layer (1) is first cut by punching in such a way that the punching line (1a) surrounds the individual drug reservoir sections (2) at an evident distance from their outer dimensions; the the resulting lattice-type refuse of the drug-free pressure-sensitive adhesive backing layer (1) is removed; and subsequently the protective layer (3) is cut in the resultant spaces between the drug reservoir sections (2).
申请公布号 NO306849(B1) 申请公布日期 2000.01.03
申请号 NO19930003414 申请日期 1993.09.24
申请人 LTS LOHMANN THERAPIE-SYSTEME GMBH & CO KG 发明人 ANHOUSER, DIETER;DEURER, LOTHAR;HILLE, THOMAS;STEINBORN, PETER
分类号 A61M37/00;A61K9/70;A61L15/44;A61M35/00;(IPC1-7):A61K9/70;A61F13/02 主分类号 A61M37/00
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