发明名称 |
Oral remedy for rheumatoid arthritis and functional food |
摘要 |
PCT No. PCT/JP96/01623 Sec. 371 Date May 18, 1998 Sec. 102(e) Date May 18, 1998 PCT Filed Jun. 13, 1996 PCT Pub. No. WO96/41644 PCT Pub. Date Dec. 27, 1996Oral drugs and functional foods of the present invention contain type-II collagen denatured (fragmented) under specific conditions. Rheumatoid arthritis (RA) has been considered to be an autoimmune disease against type-II collagen as an antigen. Since denatured type-II collagen of the invention induces high oral immune tolerance and inhibits immune responses against type-II collagen, it can prevent and treat RA. Particularly, RA can effectively be prevented and treated by simple oral administration of type-II collagen.
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申请公布号 |
US6010722(A) |
申请公布日期 |
2000.01.04 |
申请号 |
US19980981086 |
申请日期 |
1998.05.18 |
申请人 |
NIPPON MEAT PACKERS, INC. |
发明人 |
MATSUMOTO, TAKASHI;TAGUCHI, YASUKI;FUJITA, KOTARO;AMETANI, AKIO;KAMINOGAWA, SYUICHI;NAKAGAMI, MASAYO |
分类号 |
A23L1/305;A61K38/39;(IPC1-7):A61K47/42;A61K38/02 |
主分类号 |
A23L1/305 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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