Production of Drospirenone (6beta,7beta,15beta,16beta-dimethylene-3-oxo-17alpha-preg-4-en-21,17-carbolactone, DRSP), and an androstane-triol (ZK 92836) and an androstane-carbolactone (90965) as intermediates

摘要

A process for producing drospirenone (6'beta',7'beta'; 15'beta',16'beta'-dimethylene-3-oxo-17'alpha'-pregn-4-en-21,17-carbolactone, DRSP) and 7'alpha'-(3-hydroxy-1-propyl-6'beta',7'beta';15'beta',16'beta'-dimethylene-5'beta'-androstane-3'beta',5,17'beta'-triol (ZK 92836) and 6'beta',7'beta'; 15'beta',16'beta'-dimethylene-5'beta'-hydroxy-3-oxo-17'alpha'-androstane-21,17-carbolactone (ZK 90965) used as intermediates in the process.