| 发明名称 |
Attenuated forms of bovine viral diarrhea virus |
| 摘要 |
The present invention is directed to a method of producing attenuated forms of bovine viral diarrhea (BVD) virus by mutating the Npro protease gene. The invention includes the attenuated viruses made by this method, antibodies generated using these viruses, and vaccines that can be used for immunizing cattle.
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| 申请公布号 |
US6168942(B1) |
申请公布日期 |
2001.01.02 |
| 申请号 |
US19990433262 |
申请日期 |
1999.11.04 |
| 申请人 |
PFIZER INC. |
发明人 |
CAO XUEMEI;SHEPPARD MICHAEL G. |
| 分类号 |
C12N15/09;A61K31/711;A61K39/00;A61K39/12;A61K39/15;A61K39/395;A61K48/00;A61P31/12;A61P31/14;C07K14/18;C07K16/08;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/04;(IPC1-7):C12N7/04 |
主分类号 |
C12N15/09 |
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