摘要 |
An implant material in the form of a natural animal tissue crosslinked into a pre-formed shape, the tissue being adapted to substantially retain its shape when implanted into a body. Suitable tissues include fibro-serous membranes such as pericardium. Suitable crosslinking agents include aldehydes (e.g., glutaraldehyde), epoxides, isocyanates, carbodiimides, isothiocyanates, glycidalethers, and acyl azides. The implant material can be processed in either the supple or non-supple form, by the judicious use of ethanol and/or other dehydrating solutions in the course of its processing. |