| 发明名称 |
PEPTIDE-LIKE COMPOUND CONTAINING RGD SEQUENCE AND USEFUL AS INTEGRIN INHIBITOR |
| 摘要 |
<p>PURPOSE: To provide a compound capable of specifically inhibitingαvβ3 integrin. CONSTITUTION: The objective compound is expressed by formula (I) ((n) is 0, 1 ar 2). The compound has specific inhibiting activity againstαvβ3 integrin. The present invention further provides a process for the prodaction of the compound and a pharmaceutical composition conhtaining the compound and useful for the treatment of diseases caused by the abnormality of anαvβ3 integrin-interstitial cell adhesion, especially metastatic tumor.</p> |
| 申请公布号 |
KR20010049974(A) |
申请公布日期 |
2001.06.15 |
| 申请号 |
KR20000044835 |
申请日期 |
2000.08.02 |
| 申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
GIANNINI GIUSEPPE;SCOLASTICO CARLO |
| 分类号 |
A61K38/00;A61P13/12;A61P19/10;A61P27/02;A61P35/00;A61P35/04;A61P43/00;C07B53/00;C07B61/00;C07K5/00;C07K5/078;C07K5/093;C07K7/64;(IPC1-7):C07K5/00 |
主分类号 |
A61K38/00 |
| 代理机构 |
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