| 摘要 |
PROBLEM TO BE SOLVED: To produce a peptide having excellent smooth muscle relaxation action, diuretic and natriuretic activities, and hypotensive effect by transducing the below-mentioned cDNA fragments as expression vectors and developing them. SOLUTION: A cDNA fragment encoding a human cerebral natriuretic peptide containing the following amino acid sequences: Ser Pro Lys Met Val Gln Gly Ser Gly Cys Phe Gly Arg Lys Met Asp, and Arg Ile Ser Ser Ser Ser Gly Leu Gly Cys Lys Val Leu Arg Arg His. |
