摘要 |
A pharmaceutical composition for inhibiting COX-2 biosynthesis comprising a therapeutically effective amount of the compound of formula I and a pharmaceutrically acceptable carrier. <CHEM> wherein R<1> and R<4> represent either Hydrogen or together a bond R<5>, R<6>, R<7>, R<8> represent independently of each other Hydrogen, Hydroxy or Methoxy; in addition R<7> represents a sugar substituent like glucoside, rutinosid, manno gluco pyransyl, aprosylglucoside R<2> and R<3> represent Hydrogen, Hydroxy, Methoxy or <CHEM> wherein R<2>', R<3>', R<4>', R<5>' and R<6>' are independently or each other Hydrogen, Hydroxy or Methoxy with the proviso, that R<2> or R<3> is represented by the optionally substituted Phenylring. |