发明名称 |
Kinazolinderivater |
摘要 |
The invention concerns quinazoline derivatives of Formula (I) wherein Q<1 >includes a quinazoline ring optionally substituted with a group such as halogeno, trifluoromethyl and cyano, or a group of the formula: Q<3>-X<1>- wherein X<1 >includes a direct bond and O and Q<3 >includes aryl, aryl-(1-6C)alkyl, heterocyclyl and heterocyclyl-(1-6C)alkyl; each of R<2 >and R<3 >is hydrogen or (1-6C)alkyl; Z includes O, S and NH; and Q<2 >includes aryl and aryl-(1-3C)alkyl or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the prevention or treatment of T cell mediated diseases or medical conditions in a warm-blooded animal. |
申请公布号 |
NO20020042(D0) |
申请公布日期 |
2002.01.04 |
申请号 |
NO20020000042 |
申请日期 |
2002.01.04 |
申请人 |
ASTRAZENECA UK LTD |
发明人 |
CRAWLEY, GRAHAM CHARLES;MCKERRECHER, DARREN;POYSER, JEFFREY PHILIP;HENNEQUIN, LAURENT FRANCOIS ANDRE;PLE, PATRICK;LAMBERT, CHRISTINE MARIE-PAUL |
分类号 |
A61K31/47;A61K31/517;A61K31/519;A61K31/5377;A61K31/541;A61P3/10;A61P9/08;A61P9/10;A61P17/00;A61P19/02;A61P29/00;A61P37/02;A61P37/06;A61P43/00;C07D215/54;C07D239/94;C07D401/06;C07D401/12;C07D403/12;C07D417/12;C07D487/04;C07D495/04;C07D521/00;(IPC1-7):C07D |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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