POLYETHOXYLATED PYRAZOLO PYRIMIDINONE DERIVATIVES, PREPARATION PROCESS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME FOR TREATMENT OF IMPOTENCE

摘要

PURPOSE: Provided are a polyethoxylated pyrazolo pyrimidinone derivative, its pharmaceutically acceptable salt, a preparation process thereof and pharmaceutical compositions comprising the same for the treatment of impotence. CONSTITUTION: The polyethoxylated pyrazolo pyrimidinone derivative is represented by the formula(1), wherein R1 is hydrogen, C1-C6 alkyl, C3-C6 cycloalkyl substituted C1-C6 alkyl, C3-C5 cycloalkyl, C1-C3 perfluoroalkyl; C3-C6 alkenyl; or C1-C3 alkoxy C2-C6 alkyl, where the substituent is linear or branched type; and n is an integer of 2-400.