| 发明名称 |
Process for fractionating polyethylene glycol (PEG) -protein adducts and an adduct of PEG and granulocyt-macrophage colony stimulating factor |
| 摘要 |
The present invention provides adducts of polyethylene glycol and granulocyte-macrophage colony stimulating factor as well as methods for modifying a protein with pleiotropic activities which involve coupling polyethylene glycol to the protein.
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| 申请公布号 |
US6384195(B1) |
申请公布日期 |
2002.05.07 |
| 申请号 |
US19990234493 |
申请日期 |
1999.01.21 |
| 申请人 |
POLYMASC PHARMACEUTICALS PLC. |
发明人 |
DELGADO CRISTINA;FRANCIS GILLIAN ELIZABETH;FISHER DEREK |
| 分类号 |
A61K38/00;A61K31/765;A61K47/48;A61K49/00;C07K1/14;C07K14/52;C07K14/53;C07K14/535;C07K14/575;C07K14/76;C07K16/00;C07K17/08;G01N30/42;(IPC1-7):A61K38/19 |
主分类号 |
A61K38/00 |
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