发明名称 Methods for identifying a protease inhibitor
摘要 Methods are disclosed whereby inhibition of proteolytic activity causes an increase in delivery of a transferable label from a viral display package to a target cell. Assaying for the transferable label in the target cell in the presence of a test substance can identify the test substance as a protease inhibitor. Protease inhibitors so identified are used therapeutically, to treat conditions such as cancer, inflammation, rheumatoid arthritis and other autoimmune diseases, and infections, including AIDS, herpes, and hepatitis.
申请公布号 US2002072075(A1) 申请公布日期 2002.06.13
申请号 US20010791426 申请日期 2001.02.23
申请人 CHADWICK MARK P.;RUSSELL STEPHEN J. 发明人 CHADWICK MARK P.;RUSSELL STEPHEN J.
分类号 G01N33/50;C12N15/87;C12Q1/37;C12Q1/54;C12Q1/68;G01N33/15;G01N33/569;(IPC1-7):C12Q1/70;G01N33/53;G01N33/542;C12P21/04;C12P19/34;A61K39/395 主分类号 G01N33/50
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