摘要 |
There are described 4-aminobut-2-ynecarboxylic acid derivatives of formula <CHEM> wherein R1 and R2 are each independently of the other hydrogen, C1-C20alkyl; C3-C12cycloalkyl; unsubstituted or C1-C5alkyl-, C3-C12cycloalkyl-, C1-C5alkoxy-, C3-C12cycloalkoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C12cycloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl, phenyl-C1-C5alkyl, naphthyl and naphthyl-C1-C5alkyl; and R3 is C1-C20alkyl; C3-C12cycloalkyl. The compounds exhibit a pronounced activity against gram-positive and gram-negative bacteria, and also against yeasts and moulds. |
申请人 |
CIBA SPECIALTY CHEMICALS HOLDING INC. |
发明人 |
HOELZL, WERNER;HAAP, WOLFGANG;KOPPOLD, JUERGEN;OCHS, DIETMAR;PETZOLD, KARIN;SCHNYDER, MARCEL |