| 发明名称 |
Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses |
| 摘要 |
The present invention is directed to nitrosated or nitrosylated alpha-adrenergic receptor antagonists, compositions comprising alpha-adrenergic receptor antagonists that are optionally substituted with at least one NO or NO2 moiety and compounds that donate, transfer or release nitric oxide or elevate levels of endogenous endothelium-derived relaxing factor, and methods for treating sexual dysfunctions in males and females.
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| 申请公布号 |
US6417162(B1) |
申请公布日期 |
2002.07.09 |
| 申请号 |
US19990306809 |
申请日期 |
1999.05.07 |
| 申请人 |
NITROMED, INC. |
发明人 |
GARVEY DAVID S.;SCHROEDER JOSEPH D.;DE TEJADA INIGO SAENZ |
| 分类号 |
C07D295/08;A61K31/00;A61K31/131;A61K31/133;A61K31/137;A61K31/138;A61K31/145;A61K31/16;A61K31/198;A61K31/22;A61K31/222;A61K31/235;A61K31/404;A61K31/415;A61K31/4164;A61K31/4168;A61K31/417;A61K31/4174;A61K31/4178;A61K31/4375;A61K31/438;A61K31/445;A61K31/451;A61K31/475;A61K31/495;A61K31/496;A61K31/505;A61K31/506;A61K31/517;A61K38/00;A61K45/06;A61P9/00;A61P9/04;A61P9/12;A61P13/00;A61P13/08;A61P13/10;A61P15/00;A61P15/10;A61P25/28;A61P27/02;C07C217/60;C07C311/37;C07C313/08;C07C381/00;C07D211/62;C07D233/24;C07D239/95;C07D401/04;C07D405/12;C07D407/04;C07D459/00;C07D487/04;(IPC1-7):A01N43/54;A61K31/13 |
主分类号 |
C07D295/08 |
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