发明名称 |
ACRYLAMIDO DERIVATIVES USEFUL AS INHIBITORS OF THE MITOCHONDRIAL PERMEABILITY TRANSITION |
摘要 |
Acrylamido derivatives useful as therapeutic agents, particularly for the prevention and/or treatment of diseases and conditions associated with the activity of the mitochondrial permeability transition pore (MPTP), such as the diseases characterized by ischemia/reperfusion, oxidative or degenerative tissue damage, are herein described. These compounds belong to the structural formula (I)
wherein R, R', R", W and a are as defined in the specification. The invention also relates to the preparation of these compounds, as well as to pharmaceutical compositions comprising them. |
申请公布号 |
HK1164274(A1) |
申请公布日期 |
2016.11.18 |
申请号 |
HK20120105156 |
申请日期 |
2012.05.25 |
申请人 |
CONGENIA SRL |
发明人 |
FANCELLI, Daniele;VARASI, Mario;PLYTE, Simon;BALLARINI, Marco;CAPPA, Anna;CARENZI, Giacomo;MINUCCI, Saverio;PAIN, Gilles;VILLA, Manuela |
分类号 |
C07C;C07D |
主分类号 |
C07C |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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