1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof

摘要

Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I):
wherein: R 1 is hydrogen, cyano, halogen, R 8 , formyl, -C(O)R 8 , -C(O)OR 8 , -C(O)NR 9 R 10 , or -C(S)NH 2 ; R 2 is R 8 or -S(O) m R 11 ; R 3 is methyl, ethyl or C 1 -C 4 haloalkyl; R 4 , R 5 and R 7 are independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro; R 6 is halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro, -C(O)R 12 , -S(O) n R 12 or SF 5 ; Z is a nitrogen atom or C-R 13 ; R 3 is alkyl, haloalkyl, cycloalkyl or halocycloalkyl; R 9 is hydrogen, alkyl, haloalkyl or alkoxy; R 10 is hydrogen, alkyl, haloalkyl or alkoxy; R n is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; R 12 is alkyl or haloalkyl; R 13 is hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy; m is 0, 1 or 2; and n is 0, 1 or 2; or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.