Microdialysis probes and methods of use

摘要

The subject invention pertains to novel microdialysis probes having highly advantageous structural features, particularly for clinical applications. A microdialysis probe of the subject invention can be introduced into a biological tissue using insertion means such that the insertion means can the be completely dissociated from the biological tissue and the microdialysis probe. The microdialysis probes of the subject invention can further include guiding means composed of imageable material that may be used to guide the microdialysis probes to a target tissue using the appropriate sensing equipment. A further aspect of the subject invention relates to methods of using novel microdialysis probes to assess the presence or absence of a substance within biological tissue. The subject invention further relates to methods of using novel microdialysis probes to deliver a substance within biological tissue.