发明名称 |
Method for protecting cells and tissues from ionizing radiation toxicity with alpha, beta unsaturated aryl sulfones |
摘要 |
Pre-treatment with alpha,beta unsaturated aryl sulfones protects normal cells from the toxic side effects of ionizing radiation. Administration of a radioprotective alpha,beta unsaturated aryl sulfone compound to a patient prior to anticancer radiotherapy reduces the cytotoxic side effects of the radiation on normal cells. The radioprotective effect of the alpha,beta unsaturated aryl sulfone allows the clinician to safely increase the dosage of anticancer radiation. In some instances, amelioration of toxicity following inadvertent radiation exposure may be mitigated with administration of alpha,beta unsaturated arylsulfone.
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申请公布号 |
US2003060505(A1) |
申请公布日期 |
2003.03.27 |
申请号 |
US20020085745 |
申请日期 |
2002.02.28 |
申请人 |
REDDY E. PREMKUMAR;REDDY M.V. RAMANA;COSENZA STEPHEN C.;HELSON LAWRENCE |
发明人 |
REDDY E. PREMKUMAR;REDDY M.V. RAMANA;COSENZA STEPHEN C.;HELSON LAWRENCE |
分类号 |
A61K31/341;A61K31/095;A61K31/10;A61K31/275;A61K31/277;A61K31/35;A61K31/381;A61K31/40;A61K31/425;A61K31/426;A61K31/435;A61K31/4402;A61K31/4406;A61K31/4409;A61K41/00;A61P39/00;(IPC1-7):A61K31/34 |
主分类号 |
A61K31/341 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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